The film primarily takes place in Los Angeles in 1973. Frankie, a black female gogo dancer, unknowingly suffers from dissociative identity disorder, caused by a traumatic incident from her childhood (the death of a white man she was in love with, and her mother murdering her newborn when she realized the child’s father was her white lover), which she has repressed. The film begins with Frankie performing at a local strip club. She is one of the best strippers at the club, and often demands the attention of wealthy Wall Street businessmen. One night the club’s female employees go out for a “Girls Night”. As the girls observe all the men at the bar, Frankie gets the attention of a well-known bartender. She agrees to go to his home for casual sex. Before the two can engage in any sexual activity, Frankie switches to an alter ego and cracks the man’s head open with a picture frame. Word of Frankie’s violent activity spreads to the strip club quickly, and Frankie is fired from the needed job. The same manic episodes occur while Frankie is at the laundromat and a wedding. During a session with the psychiatrist Frankie learns that she has two alters: Genius, a seven-year-old child; and Alice, a Southern white racist woman, whom Frankie struggles to overcome. Through regular psychiatric sessions with her doctor, she begins to recall the traumatic events that led to her split personality. She realizes that a white man with whom she was in love died in a car accident while they were on the road. In the same session, she also uncovers the memory of the birth of her child. Moments after the birth, her mother realizes that the child is half-white and takes it away to kill it, thus triggering her personality to split.
After she watches the taped sessions and puts everything together, she begins the healing process, taking control of her life and semi-integrating the personalities that Dr. Oz assures her will always be present.